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A tissue that doesn't look good (healty), would most likely be a dying one. The concept of a cyborg itself demands a lasting solution - on the living part of it as well, since it would otherwise just be a robot with short-term living systems, but a cyborg is dependant on it's living systems as well.
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SS2 goes on in the future, where cyborgs are a reality, suggesting that those means are definitely present, so the body wouldn't even have an option of not welcoming "metal and wiring". A human body is a natural machine, a construct, a system - any system can be changed and adapted, provided that one has means to do so (information and technology). That movie isn't some kind of a realistic presentation, because the guy wasn't really stuffed with antibiotics - his makeup is irrelevant.
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The human body doesn't automaticly welcome a sudden intrusion of metal and wiring without some drastic sollutions.I don't remember that movie well, but you forgot about some things anyway: You know in the movie seven, where that one guy was stuffed with so much antibiotics to avoid infections, remember that look.
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